株式会社Rhelixa（レリクサ）

Strength
About Us
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SERVICE

Next Generation Sequencing
Bioinformatics

Cloud-based Tool RIAS®
for Medical Life Science Research

STRENGTH

Leading to Success
with high expertise and attentive service

Our professional staff will provide you
end-to-end satisfaction.

Building trustful relationships

In research support services, the success of a project cannot be achieved without building a good trust relationship with our customers. There are various situations in which researchers are extremely busy and unable to follow the rapid technological advances in omics analysis. With that in mind, Rhelixa offers support that closely aligns with the needs of researchers.

High expertise

Our company has many researchers on staff, including M.D.s and Ph.D.s. Researchers with a track record of leading large-scale projects in clinical and basic research using omics analysis will support you in experimental design, examination, and bioinformatics. Furthermore, we offer customized and integrated analysis tailored to your research objectives, rather than relying on single-process analysis pipelines in bioinformatics.

Reasonable pricing

Our lab is equipped with the highest level of research facilities, but we deliberately keep the ownership of next-generation sequencers to a minimum. This is because we believe that being tied down to "keeping the equipment running" in the increasingly diverse and complex field of omics research would make it difficult to pursue customer-oriented services that Relixa aims for. As a result, we collaborate with competitive providers both domestically and internationally in the sequencing process, achieving low-cost and high-quality data acquisition.

SUPPORTWe support all aspects of your research,

from study design to manuscript preparation and practical application.

Academic research support

Rhelixa has provided support for research published in renowned journals such as Nature Communications and EMBO.

Corporate research support

Utilizing omics information in the industrial sector leads to new product development and improved product functionality.
ビフォアサポート・データ取得・情報解析・図面作成・アフターサポート・ディスカッション
We propose the optimal plan based on the purpose, budget, and duration of your research project, and support your research and development. In addition, we offer RIAS, a cloud tool for medical and biological researchers that allows you to perform statistical analysis and create figures without the need for basic knowledge.

Co-authored Papers

Low-dose radiation induces unstable gene expression in developing human iPSC-derived retinal ganglion organoids.
Sci Rep. 2023 Aug 9;13(1):12888. doi: 10.1038/s41598-023-40051-6.
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms.
Sci Transl Med. 2023 Jun 14;15(700):eabq7721. doi: 10.1126/scitranslmed.abq7721.
A de novo genome assembly of Solanum verrucosum Schlechtendal, a Mexican diploid species geographically isolated from other diploid A-genome species of potato relatives.
G3 (Bethesda). 2022 Jul 1:jkac166. doi: 10.1093/g3journal/jkac166. Online ahead of print.
Bivalent-histone-marked immediate-early gene regulation is vital for VEGF-responsive angiogenesis.
Cell Rep. 2022 Feb 8;38(6):110332. doi: 10.1016/j.celrep.2022.110332.
Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.
Nat Commun. 2021 Dec 2;12(1):7045. doi: 10.1038/s41467-021-27321-5.
Inhibition of cardiac PERK signaling promotes peripartum cardiac dysfunction.
Sci Rep. 2021 Sep 21;11(1):18687. doi: 10.1038/s41598-021-98344-7.
PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation.
Sci Signal. 2021 Jan 26;14(667):eabb3616. doi: 10.1126/scisignal.abb3616.
Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.
EMBO J. 2020 Mar e103949. doi.org/10.15252/embj.2019103949
Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells.
Cell Rep. 2019 Oct 1;29(1):162-175.e9. doi: 10.1016/j.celrep.2019.08.086.
A de novo genome assembly of Solanum verrucosum Schlechtendal, a Mexican diploid species geographically isolated from other diploid A-genome species of potato relatives.
G3 (Bethesda). 2022 Jul 1:jkac166. doi: 10.1093/g3journal/jkac166. Online ahead of print.
Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.
Nat Commun. 2021 Dec 2;12(1):7045. doi: 10.1038/s41467-021-27321-5.
Inhibition of cardiac PERK signaling promotes peripartum cardiac dysfunction.
Sci Rep. 2021 Sep 21;11(1):18687. doi: 10.1038/s41598-021-98344-7.
PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation.
Sci Signal. 2021 Jan 26;14(667):eabb3616. doi: 10.1126/scisignal.abb3616.
Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.
EMBO J. 2020 Mar e103949. doi.org/10.15252/embj.2019103949
Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells.
Cell Rep. 2019 Oct 1;29(1):162-175.e9. doi: 10.1016/j.celrep.2019.08.086.
Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells.
Epigenetics & Chromatin 12, 77 (2019). doi.org/10.1186/s13072-019-0319-0
ChIP-Atlas: a data-mining suite powered by full integration of public ChIP-seq data.
EMBO Rep. 2018 Dec;19(12):e46255. doi:10.15252/embr.201846255
Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs.
EMBO J. 2018 Jul 2;37(13). pii: e97723. doi: 10.15252/embj.201797723.
Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch.
Nat Commun. 2018 Apr 19;9(1):1566. doi: 10.1038/s41467-018-03868-8.
Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes.
Sci Rep. 2018 Feb 28;8(1):3779. doi: 10.1038/s41598-018-22180-5.
NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.
Nat Cell Biol. 2017 Sep;19(9):1081-1092. doi: 10.1038/ncb3590.
Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation.
Nucleic Acids Res. 2017 May 5;45(8):4344-4358. doi: 10.1093/nar/gkx159.
Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.
Cell Rep. 2017 Feb 28;18(9):2228-2242. doi: 10.1016/j.celrep.2017.02.006.
H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation.
Mol Cell. 2015 Nov 19;60(4):584-96. doi: 10.1016/j.molcel.2015.10.025.
JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis.
Nat Commun. 2015 May 7;6:7052. doi: 10.1038/ncomms8052.